TrimRx
- ✓ GLP-1 options, Zepbound®, Wegovy® & Ozempic® available
- ✓ Injections and oral options are available
- ✓ 100% online process with 48-hour delivery to your home
- ✓ Flexible personalized plans, cancel anytime
Lttl
- ✓ No upcharges as your dose escalates — flat rate throughout
- ✓ Same-day clinician review; arrives in 1–2 business days
- ✓ LegitScript certified · HIPAA compliant · U.S. pharmacies
- ✓ 24/7 care team · HSA/FSA eligible · Cancel anytime
BetterMe Rx
- ✓ Oral daily tablet & injectable options — rare in this category
- ✓ Overnight free shipping · No insurance needed
- ✓ Up to 48% savings on 12-month plan · HSA/FSA eligible
- ✓ 250,000+ patients served · Cancel anytime
NewSelf
- ✓ Same price every dose — no upcharge on escalation
- ✓ 3-month supply shipped upfront — no refill delays
- ✓ Independent 3rd-party potency & sterility testing per batch
- ✓ 1,000+ board-certified physicians · Available 50 states
Gala GLP-1
- ✓ Flat $179/mo regardless of dose — full price predictability
- ✓ Providers trained at Harvard, Mount Sinai, Columbia
- ✓ Microdosing GLP-1/GIP protocol from $149/mo
- ✓ All 50 states · No insurance required · HIPAA compliant
Maximus Tribe
- ✓ Compounded AND brand-name GLP-1s from one provider
- ✓ Base-form compounds only — no unverified salt forms
- ✓ Flat-rate plan · $100 off first month on 12-month plan
- ✓ HSA/FSA accepted · Free expedited shipping · 48 states
ReadyRx
- ✓ Same-price-every-dose — no upcharges on dose escalation
- ✓ Clinician review within 24 hours of submission
- ✓ LegitScript certified · FDA-registered U.S. pharmacies
- ✓ HSA/FSA eligible · Cancel anytime · No hidden fees
Direct Meds
- ✓ Same-day shipping via FedEx/UPS — temperature controlled
- ✓ Purity analysis certificates published openly online
- ✓ Full refund if prescription not approved by clinician
- ✓ Oral sublingual drops available — needle-free option
VivioMD
- ✓ All prescribing decisions by board-certified physicians
- ✓ Flat pricing — same cost regardless of dose increase
- ✓ Named state-licensed pharmacy partners — transparent supply chain
- ✓ 24/7 care coordination · Same-day review · 49 states
Sesame Care
- ✓ Cash-pay AND insurance billing options available
- ✓ Access all major brand-name GLP-1 medications
- ✓ No subscription — pay per consultation only
- ✓ LegitScript certified · BBB accredited
Online Health Assessment
Complete a 2–5 minute intake covering your health history, goals, and current medications. No clinic visit needed.
Clinician Review
A licensed U.S. physician reviews your intake — most within 24 hours. If appropriate, a prescription is written to a licensed U.S. pharmacy.
Medication Shipped Free
Your medication is compounded by a U.S.-licensed 503A pharmacy and shipped cold-packed free to your door — typically in 1–3 days.
Ongoing Provider Support
Your provider monitors progress, adjusts dosing as needed, and supports you through the full treatment journey via patient portal messaging.
| Provider | Sema Price | Tirz Price | Oral? | Flat Dose | Delivery | LegitScript |
|---|---|---|---|---|---|---|
| TrimRx ⭐ | $179/mo | See site | ✓ | — | 48 hrs | ✓ |
| Lttl | $129/mo | $149/mo | — | ✓ | 1–2 days | ✓ |
| BetterMe Rx | $145/mo* | $215/mo* | ✓ | — | Overnight | ✓ |
| NewSelf | $99.97/mo† | $144.49/mo† | — | ✓ | 3–4 days | ✓ |
| Gala GLP-1 | $179/mo | $179/mo | — | ✓ | 2–3 days | ✓ |
| Maximus | $116/mo | $198/mo | ✓ | ✓ | Exp. | ✓ |
| ReadyRx | $149/mo | See site | — | ✓ | 1–2 days | ✓ |
| Direct Meds | $297/mo‡ | $399/mo | ✓ | ✓ | Same day | ✓ |
| VivioMD | $249/mo§ | $339/mo§ | — | ✓ | 2–4 days | ✓ |
| Sesame Care | Varies | Varies | ✓ | — | Pharmacy | ✓ |
*Annual plan rate. †3-month plan rate. ‡Standard rate; $147 promo applies first month only — verify at checkout. §Verified Feb 2026 — confirm at viviomd.com. All prices subject to change without notice.
🧬 What Is a GLP-1 Receptor Agonist?
GLP-1 is a hormone your intestine releases after eating. It signals fullness, slows gastric emptying, and regulates blood sugar. GLP-1 medications mimic this hormone — reducing appetite when combined with lifestyle changes.
⚖️ Who Typically Qualifies?
Most programs follow FDA guidelines: BMI 30+ (obesity), or BMI 27–29.9 with a weight-related condition such as type 2 diabetes, high blood pressure, high cholesterol, or sleep apnea. A licensed clinician makes the final determination.
💊 Compounded vs FDA-Approved
FDA-approved GLP-1s (Wegovy®, Zepbound®) have undergone full regulatory review. Compounded versions use the same active ingredient but are not FDA-approved products — significantly cheaper and prepared per individual prescription.
⚠️ Common Side Effects
Most common: nausea, constipation, diarrhea — especially in the first 4–8 weeks. These typically improve over time. Rare but serious: pancreatitis, gallbladder disease. Contact your provider if you experience severe abdominal pain or neck swelling.
AI-Assisted Content: This page is produced using AI-assisted research tools and publicly available clinical data, reviewed by our editorial team. It is for educational purposes only and does not constitute medical advice, diagnosis, or treatment.
Compounded Medications: Compounded semaglutide and tirzepatide are not FDA-approved products. They are prepared by licensed 503A compounding pharmacies. Individual results vary significantly.
Pricing: All prices verified from each provider's public website in August 2026 and subject to change. Always confirm the recurring rate at checkout before purchasing.
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